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KMID : 1012420150240010044
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Korean Journal of Obesity
2015 Volume.24 No. 1 p.44 ~ p.50
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Decreased Intermuscular Adipose Tissue due to Caloric Restriction in Obese Korean Women
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Park Ji-Sook
Lee Hye-Ok
Kim Young-Seol
Yim Jung-Eun
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Abstract
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Background: This study investigated the effects of caloric restriction on thigh intermuscular adipose tissue (IMAT) and the associations of IMAT and metabolic risk factors.
Methods: Thirty-three obese Korean women (BMI 27.2±2.5 kg/m2; 32.3±8.7 years) were tested before and after 12 weeks of 354.7 kcal/day dietary caloric restriction: waist circumference (WC); %fat according to bioimpedence; subcutaneous adipose tissue (SAT); visceral adipose tissue (VAT); IMAT using single-slice CT scans at the levels of L4/L5 and mid-thigh (midpoint between the anterior iliac crest and patella); fasting levels of leptin, glucose, insulin, triglycerides, total-C, LDL-C, HDL-C, and HOMA-IR. Paired t-test and Spearman correlation analysis were performed.
Results: WC, %fat, leptin, glucose, total-C, abdominal SAT and VAT, and mid-thigh IMAT decreased (P<0.05), and %change in mid-thigh IMAT correlated with %change in HOMA-IR (P<0.05).
Conclusion: Caloric restriction decreased the mid-thigh IMAT in obese Korean women, which may be correlated with reduction of metabolic risk.
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KEYWORD
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Caloric restriction, Intermuscular adipose tissue (IMAT), Obesity
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